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Chromium Polynicotinate

Chromium niacinate · ChromeMate commercial-equivalent · CAS 64452-96-6

We source, verify, and export Chromium Polynicotinate in bulk directly from top Chinese manufacturers to your port.

We provide original COA, MSDS, and other documents directly from the manufacturer with every order.

Mix-container loading, free samples (you may pay the shipment cost), and custom packaging available on request.

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Chromium Polynicotinate — bulk food ingredient sample
FDA GRAS·EU approved·JECFA·Halal · Kosher
01 — Overview

Description

An organic trivalent chromium complex with nicotinic acid (niacin) ligands, supplying approximately 10 percent elemental chromium by weight. Niacin is itself a vitamin (B3) and a documented cofactor of chromium activity in the proposed glucose tolerance factor structure.

Off-white to pale yellow free-flowing powder, slightly soluble in water. Neutral taste and odor suitable for capsule, tablet, and powdered beverage applications.

We supply food-grade Chromium Polynicotinate from manufacturers in China holding ISO, FSSC 22000, Halal, Kosher, and other certifications relevant to the product and production.

Common market grades include standard capsule and tablet powder, ChromeMate commercial-equivalent grade meeting the published clinical-trial article specification, fine-mesh grade for powdered beverages, and granulated direct-compression grade. Bulk and reduced-MOQ shipments with batch-level COA covering assay, elemental chromium, hexavalent chromium absence, heavy metals, and microbiology.

02 — Background

Introduction

Chromium polynicotinate was developed by Interhealth Nutraceuticals under the ChromeMate brand and is positioned as an alternative chromium form combining chromium with niacin, the proposed vitamin component of the glucose tolerance factor. Niacin (vitamin B3) is itself recognized for its role in glucose and lipid metabolism, contributing to the rationale for the combination.

Industrial production uses reaction of chromic chloride or chromium oxide with nicotinic acid in aqueous solution under controlled temperature and pH, followed by crystallization and drying. Strict control ensures complete absence of hexavalent chromium in the finished product.

Regulatory status includes recognition as a permitted source of chromium in food supplements under EU Regulation 1925/2006 and Directive 2002/46/EC subject to upper intake limits, and inclusion in multiple national food supplement frameworks. The compound has been studied in randomized clinical trials supporting its use in metabolic and weight management positioning.

Bioavailability of chromium from polynicotinate is comparable to or higher than picolinate in animal studies, with the niacin ligand providing additional vitamin B3 contribution at supplemental doses. The salt is positioned in the premium chromium supplement segment alongside picolinate.

03 — Applications

Where it is used

  • Glucose metabolism and insulin sensitivity supplements
  • Weight management and body composition products
  • Cardiometabolic and lipid management formulations
  • Sports nutrition products
  • Multivitamin and multi-mineral tablets
  • Functional beverages and stick-pack powders
  • Diabetes adjuvant nutrition (clinical context)
  • Senior nutrition for metabolic health
  • Pre-diabetes lifestyle support formulations
04 — Specifications

Technical data

ItemSpecification
AppearanceOff-white to pale yellow free-flowing powder
Assay (dry basis)≥ 98.0%
Elemental chromium (trivalent)9.0 to 10.5% w/w
Hexavalent chromiumNot detected (< 1 mg/kg)
Nicotinic acid content60 to 70% w/w
Loss on drying≤ 5.0%
Particle size≥ 95% through 80 mesh
Heavy metals (as Pb)≤ 5 mg/kg
Arsenic≤ 1 mg/kg
Cadmium≤ 0.5 mg/kg
Mercury≤ 0.1 mg/kg
MicrobiologyMeets food-grade limits
Shelf life36 months from manufacture under recommended storage
StorageCool, dry, sealed; protect from light
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