Yeast Beta-Glucan

A purified branched (1,3)(1,6)-beta-D-glucan recovered from the cell wall of baker's yeast (Saccharomyces cerevisiae). Distinct from oat and barley beta-glucan-cosmetic-grade-oat" class="underline" style="color: var(--sage-deep); text-decoration-color: var(--sage-deep);">beta-glucan in branching pattern and immunological activity.

Insoluble or partially soluble depending on grade. Used principally for immune-support positioning in supplements and functional foods, supported by a large body of clinical and preclinical literature on dectin-1 receptor binding.

Off-white to light cream powder. Low water solubility; dispersible with shear for use in beverage, capsule, and tablet formats.

We supply food-grade Yeast Beta-Glucan from manufacturers in China holding ISO, HACCP, Halal, Kosher, and Non-GMO Project certifications relevant to the product and production. Grades produced from primary-grown yeast and from spent brewer's yeast are both available.

Common market grades include 70 percent beta-glucan (standard supplement grade), 80 percent (premium grade), and 85 percent or higher (clinical and pharmaceutical use). Particle-size specifications run from 80 to 300 mesh; micronized grades support beverage suspension.

Bulk and reduced-MOQ shipments. Batch-level COA covering beta-glucan content, mannan and protein impurity, heavy metals, residual solvents, and microbiology.

Yeast Beta-Glucan is extracted from the inner cell wall of Saccharomyces cerevisiae, separated from outer mannoprotein and inner chitin layers through controlled alkaline-acid digestion and washing. The resulting polymer is a (1,3)-beta-D-glucan backbone with (1,6)-linked side chains, structurally distinct from the linear (1,3)(1,4) beta-glucan of oat and barley.

Source material is either primary-grown S. cerevisiae produced specifically for cell-wall fractionation, or spent brewer's yeast from the brewing industry. Primary-grown grades deliver more consistent specification and color; brewer's-derived grades are more cost-effective and carry a co-product sustainability narrative.

Regulatory status varies by jurisdiction. The U.S. FDA recognizes yeast beta-glucan as Generally Recognized as Safe via Self-Affirmation in dietary supplements and several food categories. EFSA has not issued an authorized health claim for immune function, which is why finished products in the EU rely on structure-function language rather than disease-risk claims. China's NHC recognizes yeast beta-glucan as a new food raw material.

Strategic positioning in supplement formulation is built on the dectin-1 immune-receptor mechanism and a 50-year research literature on innate-immune modulation. Against oat and barley beta-glucan, the yeast form does not deliver the viscosity-driven cholesterol or glycemic benefits but occupies an essentially separate immune-health category, often co-formulated with vitamins C and D, zinc, and elderberry in modern immune-stack products.

• Immune-support dietary supplements in capsule, tablet, and powder formats
• Functional beverages and shots positioned for immunity
• Sports and recovery nutrition
• Infant and pediatric supplements (where regulatory status permits)
• Animal nutrition and aquaculture feed for immune and gut health
• Cosmetics and topical formulations for skin barrier and anti-aging claims
• Functional dairy and yogurt
• Pharmaceutical adjuvant and excipient applications