Mannan Oligosaccharide (MOS, Yeast Cell Wall)

A prebiotic carbohydrate fraction derived from the cell wall of Saccharomyces cerevisiae (brewer's or baker's yeast). MOS binds Gram-negative pathogens through their fimbriae and carries them harmlessly through the digestive tract.

Light yellow to brown free-flowing powder with a mild yeast aroma. Highly stable to pelleting and extrusion temperatures and to the full pH range encountered in feed processing.

We supply feed-grade Mannan Oligosaccharide from manufacturers in China holding ISO, FAMI-QS, and other certifications relevant to the product and production.

Common market grades include standard 20 percent and 25 percent mannan content, and high-purity 35 percent and 45 percent for premium gut health premix use. beta-glucan-cosmetic-grade-oat" class="underline" style="color: var(--sage-deep); text-decoration-color: var(--sage-deep);">Beta-glucan content is typically reported alongside the mannan figure.

Bulk and reduced-MOQ shipments. Batch-level COA covering mannan content, beta-glucan content, protein, ash, moisture, and microbiology.

Mannan Oligosaccharide is produced by mechanical disruption and enzymatic processing of Saccharomyces cerevisiae cell walls, isolating the mannoprotein-rich outer layer that contains both alpha-mannan and beta-1,3/1,6-glucan structures.

The pathogen-binding mechanism is well characterized. Many Gram-negative bacteria carry Type 1 fimbriae with mannose-specific lectins that allow them to attach to intestinal epithelium. MOS provides an abundance of competing mannose-binding sites in the gut lumen, so the pathogens bind to the supplement instead and are excreted.

Secondary effects include immunomodulation through the beta-glucan fraction, which activates innate immune receptors on macrophages and neutrophils, and modulation of the microbiome favoring beneficial Lactobacillus and Bifidobacterium populations.

MOS is one of the longest-standing antibiotic-alternative feed additives, in commercial use since the 1990s, and has an extensive published efficacy record across all major livestock species. Approved globally as a feed material or feed additive.

• Piglet weaner feeds for pathogen binding and immune support during the post-weaning transition
• Broiler and layer feeds to bind Salmonella, E. coli, and other Gram-negative pathogens
• Calf milk replacers and starter feeds
• Aquaculture feeds for shrimp, salmonids, tilapia, and carp
• Companion animal therapeutic diets, particularly for gastrointestinal sensitivity
• Sow lactation diets to improve colostrum quality and piglet immune transfer
• Antibiotic-alternative programs in poultry and swine production
• Component of multi-active gut health and immunity premixes