Ethylparaben

The ethyl ester of p-hydroxybenzoic acid, sitting between Methylparaben and Propylparaben in both antimicrobial potency and water solubility. Selected primarily in pharmaceutical and personal-care formulations where the intermediate solubility profile is preferred.

White crystalline powder. Water solubility approximately 0.9 g/L at 20 °C; freely soluble in alcohol, propylene glycol, and oils. Effective across pH 3 to 8.

We supply food-grade and pharmaceutical-grade Ethylparaben from manufacturers in China holding ISO, Halal, Kosher and other certifications relevant to the product and production.

Common market grades include Standard Food Grade (FCC compliant), Pharmaceutical Grade meeting BP/USP/EP/JP specifications, and pre-blended paraben systems combining methyl, ethyl, and propyl parabens.

Bulk and reduced-MOQ shipments. Batch-level COA covering assay, related parabens, heavy metals, and microbiology.

Ethylparaben was developed alongside Methylparaben and Propylparaben in the original Nipa paraben series. The ethyl ester occupies a middle position in the homologous series and is less commercially significant than the methyl and propyl forms because the methyl-propyl combination already covers the practical range of water-phase and lipid-phase preservation.

Industrial production proceeds by Fischer esterification of p-hydroxybenzoic acid with ethanol under sulfuric acid catalysis, followed by neutralization, washing, and crystallization.

Regulated as E214 in the EU (with use limited to specific food categories at restricted levels), listed in BP, USP, EP, and JP pharmacopoeias, and approved by JECFA as part of the group Acceptable Daily Intake covering methyl and ethyl parabens together at 10 mg per kg body weight.

The molecule's antimicrobial mechanism and pH-independence are identical to other parabens. Activity sits between Methylparaben (weaker) and Propylparaben (stronger), and use levels are typically intermediate at 0.05 to 0.2 percent in pharmaceutical and cosmetic formulations.

Commercial use is concentrated in pharmaceutical applications where the intermediate solubility profile matches specific formulation needs, and in regional markets where Ethylparaben is preferred over Propylparaben for regulatory or consumer-perception reasons. Co-formulation with Methylparaben is standard practice.

• Pharmaceutical oral solutions, suspensions, and topical preparations
• Cosmetic and personal-care products: lotions, creams, and shampoos
• Food applications: jams, syrups, sauces, and processed fish in approved jurisdictions
• Pre-blended paraben preservative systems
• Pharmaceutical syrups and pediatric oral formulations requiring intermediate solubility
• Veterinary topical and oral pharmaceutical preparations
• Industrial water-based formulations
• Color cosmetics and lipstick preservation