Description
An organic magnesium salt of L-threonic acid (a metabolite of vitamin C), supplying approximately 8 to 9 percent elemental magnesium by weight. The salt was developed at the Massachusetts Institute of Technology and is the only magnesium compound with peer-reviewed evidence supporting brain-tissue magnesium elevation in animal models.
White to off-white free-flowing powder, freely soluble in water. Distinguished by neutral taste and excellent solubility profile relative to other organic magnesium chelates.
We supply food-grade Magnesium L-Threonate from manufacturers in China holding ISO, FSSC 22000, Halal, Kosher, and other certifications relevant to the product and production.
Common market grades include standard capsule and tablet grade, fine-mesh grade for powdered beverages, and Magtein commercial-equivalent grade meeting the published clinical-trial article specification. Bulk and reduced-MOQ shipments with batch-level COA covering assay, elemental magnesium, L-threonic acid content, heavy metals, and microbiology.
Introduction
Magnesium L-threonate was developed by researchers at the Massachusetts Institute of Technology including Guosong Liu and patented for cognitive applications based on animal studies showing the salt elevates brain tissue magnesium concentration more effectively than other magnesium forms. The Magtein commercial article is licensed by Magceutics and AIDP and is the basis of the cognitive magnesium category worldwide.
Industrial production uses oxidation of ascorbic acid (vitamin C) to L-threonic acid, followed by reaction with magnesium hydroxide or carbonate to form the magnesium chelate, with subsequent crystallization and drying. Strict control of L-threonic acid isomeric purity (less than 1 percent D-threonate) is required for the patented Magtein specification.
Regulatory status includes self-affirmed GRAS in the United States for cognitive health applications, recognition as a permitted source of magnesium in food supplements under EU regulatory frameworks (subject to safety assessment), and registration under several national food supplement frameworks in Asia-Pacific.
Bioavailability of magnesium from threonate is comparable to other organic chelates in terms of intestinal absorption, but the unique value proposition rests on the documented capacity of the salt to elevate cerebrospinal fluid and brain tissue magnesium, supporting its premium positioning for cognitive, sleep, and stress applications.
Where it is used
- Cognitive health and memory support supplements
- Sleep quality and relaxation formulations
- Stress and anxiety support products
- Premium magnesium capsules and tablets
- Nootropic and brain-health functional beverages
- Senior cognitive support supplements
- Combination cognitive and mood formulations
- Functional powders for cognitive performance
- Multi-mineral premium supplement stacks
Technical data
| Item | Specification |
|---|---|
| Appearance | White to off-white free-flowing powder |
| Assay (dry basis) | ≥ 98.0% |
| Elemental magnesium | 8.0 to 9.0% w/w |
| L-threonic acid content | 72 to 78% w/w |
| L-threonate isomeric purity | ≥ 99% L-form |
| Loss on drying | ≤ 5.0% |
| Heavy metals (as Pb) | ≤ 3 mg/kg |
| Arsenic | ≤ 1 mg/kg |
| Cadmium | ≤ 1 mg/kg |
| Mercury | ≤ 0.1 mg/kg |
| Total plate count | ≤ 1000 CFU/g |
| Salmonella | Absent in 25 g |
| Shelf life | 24 months from manufacture under recommended storage |
| Storage | Cool, dry, sealed |
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