Description
A flavone aglycone isolated from German chamomile flowers (Matricaria chamomilla), standardized to defined apigenin content. Used in sleep-support and anxiolytic dietary supplements, cosmetic skincare, and as a research-grade phytochemical.
Light yellow to yellow crystalline powder. Very limited water solubility; soluble in dilute alkali and in DMSO.
We supply food-grade Chamomile Apigenin from manufacturers in China holding ISO, Halal, Kosher and other certifications relevant to the product and production.
Common market grades include 1.2 percent Apigenin (USP-style chamomile extract), 5 percent Apigenin (standard supplement grade), 20 percent Apigenin (premium grade), and 98 percent Pure Apigenin (pharmaceutical and research grade).
Bulk and reduced-MOQ shipments. Batch-level COA covering apigenin content (HPLC), total flavonoids, residual solvents, heavy metals, pesticides, and microbiology.
Introduction
Chamomile has been used as a calming and digestive herb across European, Egyptian, and Greek traditions for over two thousand years. Apigenin is the principal flavone aglycone in chamomile flowers and the compound most directly associated with the herb's sedative and anxiolytic activity.
Industrial production proceeds by ethanol or hydroalcoholic extraction of dried chamomile flowers, followed by hydrolysis of the apigenin-7-glucoside (the predominant native form) to release apigenin aglycone, then chromatographic purification to defined grades.
Recognized as a permitted food ingredient by the U.S. FDA, the European Food Safety Authority, and equivalent regulators. Chamomile holds pharmacopoeial monograph status in EP, USP, and WHO.
Clinical evidence supports chamomile preparations for generalized anxiety disorder at appropriate doses, with mechanistic work pointing to apigenin's interaction with the benzodiazepine binding site of GABA-A receptors. Oncology research has additionally identified anti-proliferative activity in cell-culture models, supporting growing research-reagent demand.
Strategic positioning targets sleep and stress-relief dietary supplements (the dominant commercial application), with premium cosmetic skincare and research-reagent uses as secondary segments.
Where it is used
- Sleep-support dietary supplements: apigenin binds GABA-A benzodiazepine receptors at low affinity
- Anxiety and stress-relief formulations
- Premium cosmetic skincare: anti-inflammatory and anti-aging serums
- Hair-care products: scalp-soothing and pigmentation-supportive formulations
- Functional beverages: relaxation drinks and herbal teas
- Topical OTC pharmaceuticals for skin irritation
- Pharmaceutical research applications including oncology research
- Veterinary calming products for companion animals
Technical data
| Item | Specification |
|---|---|
| Appearance | Light yellow to yellow crystalline powder |
| Apigenin content (HPLC) | 1.2% / 5% / 20% / 98% (grade dependent) |
| Particle size | 95% pass 80 mesh |
| Loss on drying | ≤ 5.0% |
| Residue on ignition | ≤ 5.0% |
| Heavy metals (as Pb) | ≤ 2 mg/kg |
| Total plate count | ≤ 1000 cfu/g |
| Source | Matricaria chamomilla flowers |
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