Senna Extract Standardized

The standardized extract of Senna leaves or pods (Cassia angustifolia or Cassia acutifolia), containing sennosides as the principal active compounds. Used in pharmaceutical laxative products and traditional digestive-support dietary supplements globally.

Yellow-brown to brown free-flowing powder. Water-soluble.

We supply pharmaceutical-grade and food-grade Senna Extract Standardized from manufacturers in China holding ISO, Halal, Kosher and other certifications relevant to the product and production.

Common market grades include 8 percent Sennosides (the European Pharmacopoeia standard for senna leaf), 20 percent Sennosides (premium grade), 40 percent Sennosides (high-end concentrated grade), 60 percent Sennosides (pharmaceutical concentrate), and 98 percent Pure Sennoside A or Sennoside B (pharmaceutical-grade isolated compounds).

Bulk and reduced-MOQ shipments. Batch-level COA covering total sennosides (UV), sennoside A and B content (HPLC), residual solvents, heavy metals, pesticides, and microbiology.

Senna has been used as a laxative in Arabic, Indian, and European traditional medicine since the 9th century when Arabian physicians introduced the herb to European materia medica. The compound is among the oldest and most widely used stimulant laxatives globally.

Industrial production proceeds by hot-water extraction of dried Senna leaves or pods, followed by purification and standardization to defined sennoside content. Pharmaceutical-grade isolated sennosides A and B require chromatographic separation and crystallization.

Listed in USP, EP, BP, JP, and Chinese Pharmacopoeia as a pharmaceutical product. The European Medicines Agency has issued monographs for Senna as a herbal medicinal product for occasional constipation. Approved by the U.S. FDA as an over-the-counter laxative active ingredient. Long-term use is contraindicated due to risk of dependence and electrolyte imbalance.

The sennoside compounds are converted by colonic bacteria to rhein-anthrone, the active metabolite that stimulates colonic motility through direct action on enteric neurons. Clinical evidence supports established laxative efficacy with predictable onset of action.

Strategic positioning is dominated by pharmaceutical over-the-counter laxative products globally, with substantial secondary applications in detoxification and cleanse-positioned dietary supplements.

• Pharmaceutical laxative products: over-the-counter constipation medications globally (the dominant commercial application)
• Detoxification and cleanse-positioned dietary supplements
• Weight-management supplements (the laxative-effect-based positioning)
• Traditional herbal medicine: senna formulations across multiple medicinal traditions
• Pre-procedure bowel preparation pharmaceutical products
• Veterinary applications for digestive support
• Functional beverages: detox teas and slim-positioning drinks